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BAG1 (72-end), GST tagged human

品牌
Sigma-Aldrich
货号
SRP5165
规格纯度
recombinant, expressed in E. coli, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
参考价格
4311.28 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

BAG1 (also known as BCL2-associated athanogene) is a membrane protein rich in glutamic acid residues that binds to BCL2 and blocks apoptosis or programmed cell death. The BAG1-BCL2 complex enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Overexpression of BAG1 in 3T3 fibroblasts prevents apoptosis in the presence of low serum. BAG1 has also been shown to interact with activated glucocorticoid, androgen, estrogen and progesterone receptors. Binding to these receptors by BAG1 is dependent on receptor activation.

外形

Supplied in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.

制备说明

after opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles

基本信息

NACRESNA.32

产品性质

重组expressed in E. coli
测定≥70% (SDS-PAGE)
形式buffered aqueous glycerol solution
分子量 ~66 kDa
NCBI登记号NM_004323
运输dry ice
储存温度−70℃
Gene Informationhuman ... BAG1(573)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1

Sigma-Aldrich

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