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Azoramide

品牌
Sigma-Aldrich
CAS
932986-18-0
货号
SML1560
规格纯度
≥98% (HPLC)
参考价格
973.81 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Azoramide is a modulator of the unfolded protein response with antidiabetic activity. It has dual activity: Azoramide improves endoplasmic reticulum (ER) protein-folding ability and stimulates the expression of ER chaperones that protect cells against ER stress. Azoramide was shown to protect cells from death and dysfunction in multiple models of ER stress. It showed antidiabetic activity in two independent mouse models of obesity by improving insulin sensitivity and protecting pancreatic β cell function against ER stress.

基本信息

经验(实验)分子式C15H17ClN2OS
分子量308.83
MDL编号MFCD08009374
PubChem化学物质编号329825964

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 30 mg/mL, clear
储存温度2-8℃
SMILES stringClC1=CC=C(C2=NC(CCNC(CCC)=O)=CS2)C=C1
InChI1S/C15H17ClN2OS/c1-2-3-14(19)17-9-8-13-10-20-15(18-13)11-4-6-12(16)7-5-11/h4-7,10H,2-3,8-9H2,1H3,(H,17,19)
InChI keyVYBFWKKCWTXCQX-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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