产品说明
特点和优势
The azido-dPEG®12-NHS ester contains an azide function on one end of a single molecular weight dPEG® spacer (47.2 Å) and NHS ester group on the other end of the spacer. The dPEG® spacer is hydrophilic and non-immunogenic and improves the water solubility of the target molecule while reducing the immunogenicity and increasing the hydrodynamic volume of the target. N-hydroxysuccinimide (NHS) ester readily reacts with amines in aqueous solution or organic solvent. The azide group reacts with an alkyne in the well-known click chemistry reaction. The click chemistry reaction proceeds by copper(I) or ruthenium catalysis or in a strain-catalyzed reaction with certain types of alkyne partners.
法律信息
Products Protected under U.S. Patents # 7,888,536 B2
dPEG is a registered trademark of Quanta BioDesign
基本信息
经验(实验)分子式 | C31H56N4O16 |
分子量 | 740.79 |
MDL编号 | MFCD13184947 |
PubChem化学物质编号 | 329823933 |
产品性质
测定 | >90% |
形式 | solid or viscous liquid |
reaction suitability | reaction type: click chemistry reagent type: cross-linking reagent reaction type: click chemistry |
聚合物结构设计 | shape: linear functionality: heterobifunctional |
运输 | ambient |
储存温度 | −20℃ |
SMILES string | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])ON1C(CCC1=O)=O |
安全信息
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |