位置:首页 > 品牌 > Sigma-Aldrich >

AZD-7762 hydrochloride

品牌
Sigma-Aldrich
CAS
1246094-78-9
货号
SML0350
规格纯度
≥98% (HPLC)
参考价格
1237.51 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

应用

AZD-7762 hydrochloride has been used:

  • as a checkpoint kinase 1 and 2 (CHK1/2) inhibitor to study its effect on the efficiency of non-homologous end-joining (NHEJ) repair in breast cancer cell lines
  • as a CHK1 inhibitor to serve as a positive control for replication stress in the assessment of fork restart events
  • as a CHK1/2 inhibitor to study its effects on DNA lesions during mice zygote development

包装

5, 25 mg in glass bottle

生化/生理作用

AZD-7762 is a potent, ATP-competitive inhibitor of Chk1 and Chk2 that enhanced cytotoxicity DNA-damaging agents.

基本信息

经验(实验)分子式C17H19FN4O2S · HCl
分子量398.88
MDL编号MFCD12546135
PubChem化学物质编号329825353
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
储存条件desiccated
颜色 white to light brown
溶解性DMSO: 15 mg/mL, clear
储存温度−20℃
SMILES stringCl.NC(=O)Nc1cc(sc1C(=O)N[C@H]2CCCNC2)-c3cccc(F)c3
InChI1S/C17H19FN4O2S.ClH/c18-11-4-1-3-10(7-11)14-8-13(22-17(19)24)15(25-14)16(23)21-12-5-2-6-20-9-12;/h1,3-4,7-8,12,20H,2,5-6,9H2,(H,21,23)(H3,19,22,24);1H/t12-;/m0./s1
InChI keyWFZBLOIXZRZEDG-YDALLXLXSA-N

安全信息

象形图GHS05GHS07
警示用语:Danger
危险声明H302 - H318
预防措施声明P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
危险分类Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

推荐产品
| 首页 | 联系我们 | 会员服务 | 广告服务 | 友情链接 |
版权所有 CopyRight © 2008-2024 粤ICP备08119708号