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Anti-ZBED3 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3500033
规格纯度
affinity isolated antibody, buffered aqueous solution, ab2
参考价格
5045.46 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

免疫原

ZBED3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human ZBED3.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.

联系

The action of this antibody can be blocked using blocking peptide SBP3500033.

外形

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量predicted mol wt 26 kDa
species reactivityhuman, mouse, rat
technique(s)indirect ELISA: suitable
western blot: suitable
NCBI登记号NP_115743
UniProt登记号Q96IU2
运输dry ice
储存温度−20℃
Gene Informationhuman ... ZBED3(84327)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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