产品说明
免疫原
ZBED3 antibody was raised against a 15 amino acid peptide from near the carboxy terminus of human ZBED3.
特点和优势
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目标描述
Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.
联系
The action of this antibody can be blocked using blocking peptide SBP3500028.
外形
Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.
基本信息
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
偶联物 | unconjugated |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
形式 | buffered aqueous solution |
分子量 | predicted mol wt 26 kDa |
species reactivity | human |
technique(s) | immunocytochemistry: suitable indirect ELISA: suitable western blot: suitable |
NCBI登记号 | NP_115743 |
UniProt登记号 | Q96IU2 |
运输 | dry ice |
储存温度 | −20℃ |
Gene Information | human ... ZBED3(84327) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |