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Anti-XAF1 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1407566
规格纯度
purified immunoglobulin, buffered aqueous solution
参考价格
6644.93 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM

免疫原

XAF1 (NP_059993.2, 1 a.a. ~ 301 a.a) full-length human protein.

Sequence
MEGDFSVCRNCKRHVVSANFTLHEAYCLRFLVLCPECEEPVPKETMEEHCKLEHQQVGCTMCQQSMQKSSLEFHKANECQERPVECKFCKLDMQLSKLELHESYCGSRTELCQGCGQFIMHRMLAQHRDVCRSEQAQLGKGERISAPEREIYCHYCNQMIPENKYFHHMGKCCPDSEFKKHFPVGNPEILPSSLPSQAAENQTSTMEKDVRPKTRSINRFPLHSESSSKKAPRSKNKTLDPLLMSEPKPRTSSPRGDKAAYDILRRCSQCGILLPLPILNQHQEKCRWLASSKGKQVRNFS

外形

Solution in phosphate buffered saline, pH 7.4

基本信息

NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物unconjugated
抗体形式purified immunoglobulin
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~34.6 kDa
species reactivityhuman
technique(s)indirect immunofluorescence: suitable
western blot: 1 μg/mL
NCBI登记号NM_017523.2
UniProt登记号Q6GPH4
运输dry ice
储存温度−20℃
Gene Informationhuman ... XAF1(54739)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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