产品说明
一般描述
WASP homologue associated with actin, membranes, and microtubules (WHAMM) is a nucleation promoting factor. It is located in the cis-Golgi and tubulo-vesicular membrane transport intermediates. WHAMM contains an N-terminal region, a coiled-coil region and a WCA region. It is located on the human chromosome at 15q25.2.
特异性
Anti- WHAMM (C-terminal) recognizes human WHAMM.
免疫原
peptide corresponding to the C-terminal region of human WHAMM , conjugated to KLH.
应用
Anti-WHAMM (C-terminal) produced in rabbit may be used in immunoblotting.
生化/生理作用
WASP homologue associated with actin, membranes, and microtubules (WHAMM) takes part in actin-related protein 2 & 3 (Arp2/3)-mediated actin polymerization, mediates Golgi membrane association and microtubule dynamics. It also takes part in the maintenance of Golgi structure and participates in vesicle transport between the endoplasmic reticulum and the Golgi apparatus.
外形
Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
储存及稳定性
For continuous use, store at 2–8 ℃ for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 形式 | buffered aqueous solution |
| 分子量 | ~100 kDa |
| species reactivity | human |
| 浓度 | ~1 mg/mL |
| technique(s) | immunoblotting: 1-2 μg/mL using whole extracts of HEK-293T cells overexpressing human WHAMM. |
| UniProt登记号 | Q8TF30 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... WHAMM(123720) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
