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Anti-Tubulin β-III antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4300623
规格纯度
affinity isolated antibody
参考价格
7114.41 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The antibody detects endogenous level of total Tubulin -βIII protein.
Tubulin β-III (TUBB3) is a constituent of microtubules. It is expressed in mature neurons. It is located on human chromosome 16q24.

免疫原

Peptide sequence around aa. 442-446 (E-E-S-E-A), according to the protein NP_006077.2

应用

Anti-Tubulin β-III antibody has been used in immunocytochemistry and western blot analysis.

生化/生理作用

Upregulation of tubulin β-III (TUBB3) shows vigorous tumor characteristics and genetic instability in urinary bladder cancer. It participates in the separation of chromosome. Individuals with congenital fibrosis of the extraocular muscle type 3 (CFEOM3) show mutations in TUBB3. βIII-tubulin modulates glucose metabolism, thereby transforms glucose starvation stress signaling to develop the multiplication of cell and survival in non-small cell lung cancer cells.

特点和优势

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目标描述

Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB3 plays a critical role in proper axon guidance and mantainance.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 ~55 kDa
species reactivitymouse, human
浓度1 mg/mL
technique(s)western blot: 1:500-1:1000
同位素/亚型IgG
免疫原序列(E-E-S-E-A)
NCBI登记号NM_006086.3
运输wet ice
储存温度−20℃
Gene Informationhuman ... TUBB3(10381)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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