产品说明
一般描述
Potassium channel subfamily K member 18, also known as TWIK-related individual potassium channel or TWIK-related spinal cord potassium channel, and encoded by the gene name KCNK18 or TRESK or TRIK, is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic Tlymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction. Mutations in TRESK have been assoicated with migraine with or without aura 13.
免疫原
KLH-conjugated synthetic peptide corresponding to the center region of human TRESK.
应用
Anti-TRESK Antibody is an antibody against TRESK for use in western blotting, IHC & immunofluorescence.
Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected TRESK in rat brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TRESK in rat brain cells.
质量
Evaluated by Western Blotting in Rat brain tissue lysate.
Western Blotting Analysis: 2 μg/mL of this antibody detected TRESK in Rat brain tissue lysate.
目标描述
~40 kDa observed. Uncharacterized bands may be observed in some lysate(s).
外形
Antigen Affinity Purified
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | rat |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable western blot: suitable |
UniProt登记号 | Q7Z418 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |