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Anti-TRESK Antibody

品牌
Sigma-Aldrich
货号
ABN648
规格纯度
from rabbit, purified by affinity chromatography
参考价格
5854.74 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Potassium channel subfamily K member 18, also known as TWIK-related individual potassium channel or TWIK-related spinal cord potassium channel, and encoded by the gene name KCNK18 or TRESK or TRIK, is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic Tlymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction. Mutations in TRESK have been assoicated with migraine with or without aura 13.

免疫原

KLH-conjugated synthetic peptide corresponding to the center region of human TRESK.

应用

Anti-TRESK Antibody is an antibody against TRESK for use in western blotting, IHC & immunofluorescence.
Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected TRESK in rat brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TRESK in rat brain cells.



质量

Evaluated by Western Blotting in Rat brain tissue lysate.

Western Blotting Analysis: 2 μg/mL of this antibody detected TRESK in Rat brain tissue lysate.

目标描述

~40 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外形

Antigen Affinity Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivityrat
technique(s)immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
UniProt登记号Q7Z418
运输wet ice

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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