Anti-TREM-1, clone 2(1a2) Antibody

产品说明

一般描述

Triggering receptor expressed on myeloid cells 1 (TREM-1) is a membrane bound protein and secreted protein that is expressed by most cells in many tissues including liver, lung, spleen, lymph node, heart, and even spinal cord in response to bacterial and fungal infections. TREM-1 stimulates neutrophil and monocyte mediated inflammatory responses. TREM-1 also triggers pro-inflammatory chemokines and cytokines as well as increases surface expression of cell activation markers like CD11, thus TREM-1 acts as an amplifier of inflammatory responses in response to these pathogens. TREM-1 similarly is a potent LPS response factor and its expression is upregulated by LPS released by bacterial and fungal infections, and thus TREM-1 is a critical mediator of septic shock caused by such infections.

免疫原

Recombinant protein corresponding to human TREM-1.

应用

Research Sub Category
Immunoglobulins & Immunology
This Anti-TREM-1, clone 2(1a2) Antibody is validated for use in Flow Cytometry for the detection of TREM-1.
Research Category
Inflammation & Immunology

质量

Evaluated by Flow Cytometry in human peripheral blood mononuclear.

Flow Cytometry Analysis: 0.25 µg of this antibody detected TREM-1 in human peripheral blood mononuclear cells.

目标描述

26 kDa calculated

外形

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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