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Anti-TDP2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4301078
规格纯度
affinity isolated antibody
参考价格
5097.31 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Tyrosyl DNA phosphodiesterase-2 (TDP2) is a multi-functional protein and is also called as TTRAP (TNF receptor-associated protein). It is a 5- tyrosyl DNA phosphodiesterase that belongs to the PML NB (promyelocytic leukemia nuclear body) protein family. TDP2 is mapped to human chromosome 6p22.

特异性

The antibody detects endogenous levels of total TDP2 protein.

免疫原

Synthetic peptide corresponding to a region derived from internal residues of human tyrosyl-DNA phosphodiesterase 2

生化/生理作用

Chromosomal translocations stimulated by DNA topoisomerase II at the time of gene transcription is repressed by tyrosyl DNA phosphodiesterase-2 (TDP2). It is essential to preserve the chromosome stability in human cells. TDP2 participates in cell proliferation, apoptosis and the repair of DNA damage. It promotes cell cycle arrest and apoptosis in osteosarcoma cells.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 41 kDa
species reactivityhuman, mouse
浓度2.6 mg/mL
technique(s)immunohistochemistry: 1:50- 1:200
western blot: 1:200-1:1000 (Cell Lysate)
同位素/亚型IgG
登记号NP_057698.2
UniProt登记号O95551
运输wet ice
储存温度−20℃
Gene Informationhuman ... TDP2(51567)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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