产品说明
一般描述
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
免疫原
Linear peptide corresponding to the C-terminus of human SOX9.
应用
Research Sub Category
Transcription Factors
Anti-SOX9 Antibody is a highly specific rabbit polyclonal antibody, that targets SOX9 & has been tested in western blotting, IHC & Immunofluorescence.
Immunohistochemistry Analysis: A representative lot from an independent laboratory detected SOX9 in K14 mouse backskin tissue (Nowak, J. A., et al. (2008). Cell Stem Cell. 3(1):33-43.).
Immunofluorescence Analysis: A representative lot from an independent laboratory detected SOX9 in mouse Label Retaining cells, and developing epithelial skin and hair follicle cells (Nowak, J. A., et al. (2008). Cell Stem Cell. 3(1):33-43.).
Research Category
Epigenetics & Nuclear Function
质量
Evaluated by Western Blotting in NIH/3T3 cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected SOX9 in 10 µg of NIH/3T3 cell lysate.
目标描述
~63 kDa observed. Uncharacterized band(s) may be observed in some cell lysates.
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse |
species reactivity (predicted by homology) | rat (based on 100% sequence homology), human (based on 100% sequence homology) |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable western blot: suitable |
NCBI登记号 | NP_000337 |
UniProt登记号 | P48436 |
运输 | wet ice |
Gene Information | human ... SOX9(6662) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |