产品说明
一般描述
Somatotropin (UniProt P01241; also known as GH, GH-N, Growth hormone 1, hGH-N, Pituitary growth hormone) is encoded by the GH1 (also known as GH, GHN, IGHD1B) gene (Gene ID 8856) in human. Somatotropin is a peptide hormone that plays an important role in growth control by inducing IGF-1 secretion in liver and other tissues. It stimulates myoblast differentiation and proliferation, as well as amino acids uptake and protein synthesis in muscle and other tissues. Acromegaly is a rare endocrine syndrome caused by a GH-secreting pituitary adenoma. Acromegaly may also be rarely associated with a hypothalamic or an ectopic GH-releasing hormone-producing tumor.
特异性
Expected to react with isoforms 1, 3, and 4. Reactivity to isoforms 2 and 5 have not been tested.
免疫原
GST-tagged recombinant protein corresponding to human Somatotropin/GH1.
应用
Research Sub Category
Apoptosis - Additional
Anti-Somatotropin/GH1 Antibody, clone 1H1.1 is an antibody against Somatotropin/GH1 for use in Western Blotting.
Research Category
Apoptosis & Cancer
质量
Evaluated by Western Blotting in human pituitary tissue lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Somatotropin/GH1 in 10 µg of human pituitary tissue lysate.
目标描述
~25 kDa observed. This protein has several isoforms from ~20-25 kDa
外形
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Format: Purified
Protein G Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 1H1.1, monoclonal |
species reactivity | human |
technique(s) | western blot: suitable |
同位素/亚型 | IgG1κ |
NCBI登记号 | NP_000506 |
UniProt登记号 | P01241 |
运输 | wet ice |
Gene Information | human ... GH1(2688) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |