产品说明
一般描述
The sodium-coupled neutral amino acid transporter 3 (SLC38A3) protein is a sodium-dependent amino acid/proton exchanger (also called an antiporter or counter transporter) SLC38A3 mediates the electrogenic cotransport of glutamine and sodium ions in exchange for protons. SLC38A3 can also transport the amino acids histidine, asparagine and alanine in place of protons. Some evidence exists that SLC38A3 may mediate amino acid transport in either direction under particular physiological conditions such as homeostatic stress like that seen in acidosis, and SLC38A3 plays a role in nitrogen metabolism and synaptic transmission by regulating the levels of sodium and the stimulatory amino acid glutamine. SLC38A3 is localized to the cell membrane and is widely expressed in many tissues, including heart, liver, brain, and prostate.
免疫原
GST-tagged recombinant protein corresponding to human SLC38A3.
应用
Research Category
Neuroscience
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected SLC38A3 in human kidney tissue.
Research Sub Category
Developmental Signaling
Anti-SLC38A3 Antibody, clone 1A10.2 | MABN316 is an antibody against SLC38A3 Antibody for use in Western Blotting, Immunohistochemistry.
质量
Evaluated by Western Blotting in human kidney tissue lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected SLC38A3 in 10 µg of human kidney tissue lysate.
目标描述
~60 kDa observed
外形
Format: Purified
Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Protein G Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | mouse |
| 抗体形式 | purified antibody |
| antibody product type | primary antibodies |
| 克隆 | 1A10.2, monoclonal |
| species reactivity | human |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| 同位素/亚型 | IgG2aκ |
| NCBI登记号 | NP_006832 |
| UniProt登记号 | Q99624 |
| 运输 | wet ice |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
