产品说明
一般描述
Solute carrier family 12 member 3 (SLC12A3) is also known as thiazide-sensitive Na+-Cl- cotransporter (NCCT). It is expressed in the apical cells of the distal convoluted tubule. The gene encoding this 1021 amino acid protein is localized on human chromosome 16q13. The gene ID for the protein is 6559.
特异性
Detects ~160 kDa.
免疫原
AA74-95 (rat), 76-97 (hum)
生化/生理作用
Solute carrier family 12 member 3 (SLC12A3) is one of the major components of the sodium chloride reabsorption pathway. It controls the Cl- concentration and is also involved in the transepithelial ion absorption and secretion. Mutations in the gene encoding SLC12A3 have been associated with Gitelman syndrome.
This Na-Cl cotransporter is associated with maintaining blood pressure.
特点和优势
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外形
PBS, 50% glycerol, and 0.09% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous glycerol solution |
| 分子量 | antigen predicted mol wt 160 kDa |
| species reactivity | mouse, rat, human |
| 浓度 | 1 mg/mL |
| technique(s) | western blot: suitable |
| NCBI登记号 | NP_000330 NP_062218 |
| UniProt登记号 | P55017 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SLC12A3(6559) rat ... Slc12a3(54300) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
