产品说明
一般描述
SLC1A1 (also known as EAAC1, EAAT3) is localized at the postsynaptic site of neurons. It is expressed at moderate levels in the adult brain, mainly in the hippocampus, basal ganglia and olfactory bulb and is considered to make a minor contribution to glutamate removal from the synapse.
免疫原
synthetic peptide corresponding to a sequence near the C-terminus of human SLC1A1, conjugated to KLH. The corresponding sequence is identical in mouse and rat SLC1A1.
应用
Anti-SLC1A1 antibody produced in rabbit has been used in immunohistochemistry and immunoblotting.
生化/生理作用
SLC1A1 regulates the developmental effects of glutamate. It is highly regulated by neural activity and intracellular signaling pathways involving mainly PKCa, PI3K, and glial factors, resulting in rapid changes in the trafficking of the transporter and in its membrane location.
外形
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen ~70 kDa |
| species reactivity | mouse, human |
| 增强验证 | recombinant expression Learn more about Antibody Enhanced Validation |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunohistochemistry: 10-20 μg/mL using formalin-fixed paraffin-embedded human small intestine. western blot: 1.5-3.0 μg/mL using Neuro-2a cell extracts. |
| UniProt登记号 | P43005 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SLC1A1(6505) mouse ... Slc1a1(20510) rat ... Slc1a1(25550) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
