产品说明
一般描述
Monoclonal Anti-Septin 9 (rat IgG2a isotype) is derived from the hybridoma 1A6C2 produced by the fusion of mouse myeloma cells and splenocytes from rat immunized with a synthetic peptide of corresponding to the N-terminus of rat Septin 9, conjugated to KLH. Septin 9 (SEPT9) is a member of the septin family (also designated MSF/eseptin/Sint1). This gene is mapped to human chromosome 17q25.
免疫原
synthetic peptide of corresponding to the N-terminus of rat Septin 9 conjugated to KLH
应用
Monoclonal Anti-Septin 9 has been used in:
- immunoblotting
- immunocytochemistry
- immunohistochemistry
- immunofluorescence
生化/生理作用
Septin 9 (SEPT9) has been implicated in tumorigenesis. Mutations in this gene cause hereditary neuralgic amyotrophy, also known as neuritis with brachial predilection. In addition, SEPT9 is shown to be a DNA methylation-based biomarker, effectively discriminated colorectal cancer from normal specimens.
外形
Solution in 0.01M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rat |
| 偶联物 | unconjugated |
| 抗体形式 | purified from hybridoma cell culture |
| antibody product type | primary antibodies |
| 克隆 | Clone 1A6C2, monoclonal |
| 形式 | buffered aqueous solution |
| 分子量 | ~72 kDa |
| species reactivity | monkey, rat, mouse, human |
| 浓度 | ~1.0 mg/mL |
| technique(s) | immunocytochemistry immunohistochemistry western blot: 2.5-5.0 μg/mL using L929, HeLa, 3T3 and COS-7 cell extracts |
| 同位素/亚型 | IgG2a |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... SEPT9(10801) mouse ... Sept9(53860) rat ... Sept9(83788) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
