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Anti-SCRN1 Antibody

品牌
Sigma-Aldrich
货号
ABC829
规格纯度
from rabbit, purified by affinity chromatography
参考价格
5854.74 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Secernin-1 (SCRN1) is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.

免疫原

KLH-conjugated synthetic peptide corresponding to the C-terminus of human SCRN1.
Epitope: C-terminus

应用

Research Sub Category
Apoptosis - Additional
Anti-SCRN1 Antibody is an antibody against SCRN1 for use in western blotting, IHC & immunofluorescence.
Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected SCRN1 in human kidney tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected SCRN1 in human kidney cells.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in human kidney tissue with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected SCRN1 in human kidney tissue with and without blocking peptide.

目标描述

~30 and ~48 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
纯化方式affinity chromatography
species reactivityhuman
technique(s)immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable
UniProt登记号Q12765
运输wet ice
Gene Informationhuman ... SCRN1(9805)

安全信息

储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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