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Anti-SARS-CoV-2 (COVID-19) Membrane antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3501134
规格纯度
affinity isolated antibody
参考价格
4802.96 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus. The disease is the cause of the 2019–20 coronavirus outbreak. SARS-CoV-2 is the seventh member of the enveloped, positive-stranded RNA viruses that are able to infect humans. The SARS-CoV-2 genome, like other coronaviruses, encodes for multiple structural and nonstructural proteins. The structural proteins include spike protein (S), envelope protein (E), membrane glycoprotein (M), nucleocapsid phosphoprotein (N), and the nonstructural proteins include open reading frame 1ab (ORF1ab), ORF3a, ORF6, ORF7a, ORF8, and ORF10.The membrane (M) protein or matrix protein is the most abundant structural protein and defines the shape of the viral envelope. It is an integral membrane protein involved in the budding of the viral particles and interacts with S (Spike) protein. It involves in organization of the nucleoprotein inside, which includes many copies of the N (nucleocapsid) protein bound to the genomic RNA. The M protein holds dominant cellular immunogenicity and has been determined as a protective antigen in humoral responses, which suggests it would serve as a potential target in vaccine design.

免疫原

Anti-SARS-CoV-2 (COVID-19) Membrane antibody was raised against a peptide corresponding to 15 amino acids near the carboxyl terminus of SARS-CoV-2 (COVID-19) Membrane protein. The immunogen is located within the last 50 amino acids of SARS-CoV-2 (COVID-19) Membrane protein.

应用

Antibody validated: Immunohistochemistry in human samples. SARS-CoV-2 (COVID-19) Membrane antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 Membrane recombinant protein by ELISA and WB. All other applications and species not yet tested.

外形

Supplied in PBS containing 0.02% sodium azide.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式liquid
species reactivitySARS coronavirus
浓度1 mg/mL
technique(s)ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
同位素/亚型IgG
运输wet ice
储存温度−20℃
Gene InformationSARS coronavirus ... M(43740571)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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