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Anti-PSPC1 (C-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200067
规格纯度
~1.0 mg/mL, affinity isolated antibody
参考价格
6784.15 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

PSPC1 has two isoforms α and β.
Paraspeckle component 1 (PSPC1) is encoded by the gene mapped to human chromosome 13q12.11. The encoded protein is a member of DBHS (Drosophila Behavior Human Splicing) family of proteins.

应用

Anti-PSPC1 (C-terminal) antibody produced in rabbit has been used in:

  • immunoblotting
  • ribonucleoprotein immunoprecipitation assay
  • immunofluorescence
  • immunocytochemistry

生化/生理作用

Paraspeckle component 1 (PSPC1) is involved in the regulation of nuclear receptors such as the progesterone receptor and the thyroid receptor and in a wide range of processes such as splicing and RNA metabolism.
Since paraspeckle component 1 (PSPC1) has lower background nucleoplasmic signal in various cell types compared to other members of DBHS (drosophila behavior human splicing) family of proteins, it is frequently used as a marker for paraspeckles. The encoded protein plays a vital role in regulation of transcription. Deletion of the gene is associated with the hindered psychomotor development, muscle hypotonia, unilateral microphtalmia with ptosis, congenital eye malformation and facial dysmorphic features.

外形

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen ~45 kDa
antigen ~59 kDa
species reactivityhuman
浓度~1.0 mg/mL
technique(s)immunoprecipitation (IP): 2.5-5 μg using lysates of HEK-293T cells
indirect immunofluorescence: 1.25-2.5 μg/mL using paraformaldehyde fixed HEK-293T cells
western blot: 0.5-1 μg/mL using lysates of HEK-293T cells
UniProt登记号Q8WXF1
运输dry ice
储存温度−20℃
Gene Informationhuman ... PSPC1(55269)
mouse ... Pspc1(66645)
rat ... Pspc1(305910)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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