产品说明
一般描述
Patatin like phospholipase domain containing 3 (PNPLA3) gene is mapped to human chromosome 22q13.3. The protein encoded by this gene is a triacylglycerol lipase.
免疫原
PNPLA3 (AAH65195.1, 1 a.a. ~ 481 a.a) full-length human protein.
Sequence
MYDAERGWSLSFAGCGFLGFYHVGATRCLSEHAPHLLRDARMLFGASAGALHCVGVLSGIPLEQTLQVLSDLVRKARSRNIGIFHPSFNLSKFLRQGLGKCLPANVHQLISGKIGISLTRVSDGENVLVSDFRSKDEVVDALVCSCFMPFYSGLIPPSFRGVRYVDGGVSDNVPFIDAKTTITVSPFYGEYDICPKVKSTNFLHVDITKLSLRLCTGNLYLLSRAFVPPDLKVLGEICLRGYLDAFRFLEEKGICNRPQPGLKSSSEGMDPEVAMPSWANMSLDSSPESAALAVRLEGDELLDHLRLSILPWDESILDTLSPRLATALSEEMKDKGGYMSKICNLLPIRIMSYVMLPCTLPVESAIAIVQRLVTWLPDMPDDVLWLQWVTSQVFTRVLMCLLPASRSQMPVSSQQASPCTPEQDWPCWTPCSPEGCPAETKAEATPRSILRSSLNFFLGNKVPAGAEGLSTFPSFSLEKSL
应用
Anti-PNPLA3 antibody produced in rabbit has been used in western blotting.
生化/生理作用
PNPLA3 (patatin like phospholipase domain containing 3) involves lipogenic transacetylase activity. Variation in PNPLA3 (patatin like phospholipase domain containing 3) is known to increase the fat content of hepatocytes, thereby promoting the severity of nonalcoholic liver disease. The gene is found to be associated with hepatic steatosis, liver fibrosis and cancer. PNPLA3 might be involved in energy homeostasis. PNPLA3 mediates triacylglycerol hydrolysis in adipocytes and is involved in the balance of energy usage cum storage in adipocytes.
PNPLA3 mediates triacylglycerol hydrolysis in adipocytes and is involved in the balance of energy usage cum storage in adipocytes.
外形
Solution in phosphate buffered saline, pH 7.4
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | mouse, human |
| technique(s) | western blot: 1 μg/mL |
| NCBI登记号 | BC065195.1 |
| UniProt登记号 | Q9NST1 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PNPLA3(80339) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
