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Anti-PML Sumoylation Site antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1300291
规格纯度
IgG fraction of antiserum, buffered aqueous solution
参考价格
4578.18 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

PML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL).

免疫原

PML (NP_150242, 474-509)
This antibody is generated from rabbits immunized with the KLH conjugated synthetic peptide PRKVIKMESEEGKEA containing a predicted sumoylation site from the central region of human PML.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
偶联物unconjugated
抗体形式IgG fraction of antiserum
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityhuman
technique(s)immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500
NCBI登记号NP_150242
UniProt登记号P29590
运输dry ice
储存温度−20℃

安全信息

储存分类代码12 - Non Combustible Liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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