产品说明
一般描述
The PLD1 (phospholipase D1) gene is mapped to human chromosome 3q26.31. The protein encoded consists of pleckstrin homology and phox homology domains.
Anti-PLD1 Antibody detects endogenous levels of total PLD1 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human PLD1.
Immunogen Range: 527-576
生化/生理作用
PLD1 (phospholipase D1) is responsible for the hydrolysis of phosphatidylcholine to yield phosphatidic acid and choline. It controls EGFR (epidermal growth factor receptor) endocytosis, which is associated with the process of cell proliferation, differentiation, migration and survival. PLD1 regulates the metabolic flexibility of cancer cells to help it maintain its viability and proliferation in response to stress. Upregulation of the gene is observed in gastric cancer. PLD1 might play an important role in allergic disorders such as asthma.
特点和优势
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外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 124 kDa |
| species reactivity | mouse, human, rat |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:1000 immunohistochemistry: 1:50-1:100 |
| NCBI登记号 | Q13393 |
| UniProt登记号 | Q13393 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PLD1(5337) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
