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Anti-Phospho-STAT3-S727 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701791
包装型号
规格纯度
参考价格
4266.29 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]

免疫原

A synthesized peptide derived from human Phospho-Phospho-STAT3-S727 (S727).

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityhuman
浓度1.48 mg/mL
technique(s)western blot: 1:500-1:2000
UniProt登记号P40763
运输wet ice
储存温度−20℃
Gene Informationhuman ... STAT3(6774)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

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