产品说明
一般描述
The protein encoded by this gene is found as a pentamer and is a major substrate for the cAMP-dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+)-ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the inotropic response elicited in heart by beta-agonists. The encoded protein is a key regulator of cardiac diastolic function. Mutations in this gene are a cause of inherited human dilated cardiomyopathy with refractory congestive heart failure, and also familial hypertrophic cardiomyopathy.
免疫原
A synthetic phosphorylated peptide around of human Phospho-PLN-S16/T17.
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | mouse, human |
| 浓度 | 0.84 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt登记号 | P26678 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... PLN(5350) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
