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Anti-phospho-p47 phox (pSer359) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4504289
规格纯度
affinity isolated antibody
参考价格
6418.39 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Phospho-p47/ NCF1 (neutrophil cytosolic factor-1) codes for the p47phox subunit of the phagocyte NADPH oxidase (NOX2). It is a cytosolic factor. This gene is located with two pseudogenes (NCF1B and NCF1C). NCF1 is mapped to human chromosome 7q11.23.

免疫原

The antiserum was produced against synthesized peptide derived from human p47 phox around the phosphorylation site of Ser359.

Immunogen Range: 331-380

生化/生理作用

NCF1 (neutrophil cytosolic factor-1) is an important constituent of the phagocyte NADPH-oxidase system. The enzyme helps in the synthesis of microbicidal superoxide in phagocytes like neutrophil and plays a key role in host defense against microbial pathogens. A 2-bp GT deletion in exon 2 of the NCF1 gene results in chronic granulomatous disease (CGD).

特点和优势

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外形

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

生物来源rabbit
质量水平100
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量antigen 44 kDa
species reactivitymouse, rat, human
浓度~1 mg/mL
technique(s)ELISA: 1:5000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号P14598
UniProt登记号P14598
运输wet ice
储存温度−20℃
Gene Informationhuman ... NCF1(653361)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

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