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Anti-Phospho-JNK1/2/3-T183/T183/T221 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701783
包装型号
规格纯度
参考价格
5406.77 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Apr 2016]

免疫原

A phospho specific peptide corresponding to residues surrounding T183/T183/T221 of human JNK1/2/3

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityrat, human, mouse
浓度1.61 mg/mL
technique(s)immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000
UniProt登记号P45983/P45984/P53779
运输wet ice
储存温度−20℃

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

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