产品说明
一般描述
This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
免疫原
A phospho specific peptide corresponding to residues surrounding S118 of human Estrogen Receptor alpha (ESR1)
外形
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | monoclonal |
| 形式 | liquid |
| species reactivity | human |
| 浓度 | 1.5 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt登记号 | P03372 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... ESR1(2099) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
