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Anti-Phospho-CHEK1-S280 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5700286
包装型号
规格纯度
参考价格
4713.83 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.

免疫原

A synthetic phosphorylated peptide around S280 of human CHEK1 (NP_001265.2).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

产品性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 43
50
54
species reactivityhuman, mouse, rat
浓度1.66 mg/ml
technique(s)immunofluorescence: 1:50-1:200
immunohistochemistry: 1:50-1:200
western blot: 1:200-1:2000
UniProt登记号O14757
运输wet ice
储存温度−20℃
Gene Informationhuman ... CHEK1(1111)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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