产品说明
一般描述
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
免疫原
A synthetic phosphorylated peptide around Y14 of human Caveolin-1 (NP_001744.2).
外形
Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | liquid |
| species reactivity | rat, mouse, human |
| 浓度 | 1.59 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt登记号 | Q03135 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... CAV1(857) |
安全信息
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
