产品说明
一般描述
CD31, also known as platelet endothelial cell adhesion molecule 1 (PECAM1) is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction.
应用
Anti-PECAM-1 Antibody, clone 390 is an antibody against PECAM-1 for use in FC, IH & IP.
Flow Cytometry: 1 μg/10e6 cells.
Immunohistochemistry: acteone fixed frozen tissue sections
Immunoprecipitation
Blocking of cell adhesion: CBL1337 inhibits aggregation of L cells transfected with a variant form of CD31 (DeLisser, 1993)
Optimal working dilutions must be determined by the end user.
外形
Protein A purified
Protein A Purified mouse immunoglobulin in 100mM borate buffered saline, pH 8.0, containing no preservative.
Format: Purified
分析说明
Control
Jurkat and Raji cells, tonsil tissue
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
产品性质
| 质量水平 | 100 |
| 生物来源 | rat |
| 抗体形式 | purified immunoglobulin |
| antibody product type | primary antibodies |
| 克隆 | 390, monoclonal |
| species reactivity | mouse |
| manufacturer/tradename | Chemicon® |
| technique(s) | flow cytometry: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable |
| 同位素/亚型 | IgG2aκ |
| NCBI登记号 | NM_000442.3 |
| UniProt登记号 | P16284 |
| 运输 | wet ice |
| Gene Information | human ... PECAM1(5175) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
