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Anti-Parvin alpha Antibody, clone 7E2.1

品牌
Sigma-Aldrich
货号
MABT157
规格纯度
clone 7E2.1, from mouse
参考价格
5052.86 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The protein named α-Parvin or Parvin, or Actopaxin, or Calponin-like integrin-linked kinase-binding protein (CH-ILKBP), or Matrix-remodeling-associated protein 2 (MXRA2), and encoded by the gene PARVA/MXRA2, is a critical adhesion coupling protein involved in many systems including sarcomere organization, smooth muscle contraction, cardiovascular development, angiogenesis, actin cytoskeleton organization and the establishment of cell polarity, adhesion, spreading and migration. α-Parvin is required for the adhesion of smooth muscle cell to endothelial cells during blood vessel development and for the formation of lamellipodia and ciliogenesis. α-Parvin is localized to the cell junction and focal adhesions. The protein is peripheral membrane protein located on the cytoplasmic side of the cell membranes and interacts with the cytoskeleton in the cytoplasm. In muscle cells it is associated with the Z line of the sarcomere. α-Parvin is expressed many tissues including muscle, kidney and liver.

免疫原

GST-tagged recombinant protein corresponding to human Parvin.

应用

This Anti-Parvin alpha Antibody, clone 7E2.1 is validated for use in western blotting & IHC (Paraffin) for the detection of Parvin alpha.
Immunohistochemistry Analysis: A 1:2,000 dilution and a 1:50 dilution from a representative lot detected Parvin alpha in human kidney and skeletal muscle tissues, respectively.

质量

Evaluated by Western Blotting in human heart tissue.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected Parvin alpha in 200 µg of human heart tissue.

目标描述

~42 kDa observed

外形

Protein G Purified
Format: Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
抗体形式purified antibody
antibody product typeprimary antibodies
克隆7E2.1, monoclonal
species reactivityhuman
technique(s)immunohistochemistry: suitable (paraffin)
western blot: suitable
同位素/亚型IgG1κ
NCBI登记号NP_060692
UniProt登记号Q9NVD7
运输wet ice
Gene Informationhuman ... PARVA(55742)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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