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Anti-NRAS (internal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200778
规格纯度
affinity isolated antibody
参考价格
6567.14 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

NRAS, also known as GTPase NRas, Transforming protein N-Ras, or Neuroblastoma RAS Viral (V-Ras) Oncogene Homolog, is a member of the Ras protein family, together with KRAS (Kirsten RAS), and HRAS (Harvey RAS), comprising a family of low-molecular-weight GTPases. The Ras family is named for a retrovirus that induced rat sarcomas that were later found to have activating RAS mutations. Ras family proteins serve as molecular switches in regulating pathways that are responsible for diverse cellular processes such as proliferation, differentiation, migration, and apoptosis.3 Ras proteins are highly homologous regarding their primary amino acid sequence and the differences among them concentrated in their C-terminal region. Anti-NRAS (internal) antibody produced in rabbit specifically recognizes human NRAS and does not cross-react with KRAS.

免疫原

Synthetic peptide from the internal region of human NRAS protein, conjugated to KLH

应用

The antibody may be used in various immunochemical techniques including immunoblotting (predicted ∼21 kDa) and immunohistochemistry. Detection of the NRAS band by Immunoblotting is specifically inhibited by the immunizing protein.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide as preservative.

其他说明

This product is for R&D use only, not for drug, household, or other uses.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量predicted mol wt ~21 kDa
species reactivityhuman
浓度~1.0 mg/mL
technique(s)immunoblotting: 2.5-5 μg/mL using human MCF7 cell line extract
immunohistochemistry: 10-20 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human melanoma sections
UniProt登记号P01111
运输dry ice
储存温度−20℃
Gene Informationhuman ... NRAS(4893)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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