产品说明
一般描述
Neurexins are heavily glycosylated and processed neuronal transmembrane cell surface proteins likely involved in cell recognition and adhesion. (Missler, M., et al. (1998) 14(1):20-26) Antibody Anti-neurexin 3 alpha (ABN96) was made against a peptide immunogen corresponding to a stretch of amino acids in the extracellular domain of human neurexin 3 alpha (Uniprot Q9Y4C0). Although the theoretical full length of Neurexin 1alpha is 180 kDa, the protein detected in human brain lysates may show a band around 180 kDa and additional bands around 40-55 kDa as a possible result of the posttranslational processing previously reported.
免疫原
KLH-conjugated linear peptide corresponding to human Neurexin-3.
应用
Detect Neurexin3 using this Anti-Neurexin3 Antibody validated for use in WB, IH.
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Neurexin-3 in normal mouse brain tissue.
Research Category
Neuroscience
Research Sub Category
Neurodegenerative Diseases
质量
Evaluated by Western Blot in PC12 cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected Neurexin-3 in 10 µg of PC12 cell lysate.
目标描述
~180 kDa observed. UniProtKB/Swiss-Prot Q9Y4C0 (NRX3A_HUMAN) states 2 isoforms due to alternative promoter usage and alternative splicing at a molecular weight of ~181 kDa and ~117 kDa, with several beta isoforms at a molecular weight 70 kDa, 51 kDa, 47 kDa, and 44 kDa Additional bands may also be observed around 40-55 kDa as a possible result of the posttranslational processing.
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
PC12 cell lysate.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse, rat, human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
NCBI登记号 | NP_004787 |
UniProt登记号 | Q9Y4C0 |
运输 | wet ice |
Gene Information | human ... NRXN3(9369) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |