产品说明
一般描述
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
免疫原
DNMT3L (Q9CWR8, 393-431)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the mouse Dnmt3L sequence within the last 100 aa. The antibody may recognize the human homolog (44 kDa).
外形
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
产品性质
| 生物来源 | rabbit |
| 质量水平 | 200 |
| 偶联物 | unconjugated |
| 抗体形式 | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| species reactivity | mouse |
| technique(s) | indirect ELISA: 1:1000 |
| NCBI登记号 | NP_037501 |
| UniProt登记号 | Q9UJW3 |
| 运输 | dry ice |
| 储存温度 | −20℃ |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
