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Anti-Mast Cell Tryptase (TPSB2) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB5701372
包装型号
规格纯度
参考价格
4668.88 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3' UTR and contain tandem repeat sequences at the 5' flank and 3' UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, beta II and beta III. Beta tryptases appear to be the main isoenzymes expressed in mast cells, whereas in basophils, alpha-tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]

免疫原

A synthesized peptide derived from human Mast Cell Tryptase (TPSB2) (TPSB2)

外形

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

产品性质

生物来源rabbit
质量水平100
antibody product typeprimary antibodies
克隆monoclonal
形式liquid
species reactivityhuman
浓度0.48 mg/mL
technique(s)immunohistochemistry: 1:50-1:200
western blot: 1:1000-1:3000
UniProt登记号P20231
运输wet ice
储存温度−20℃
Gene Informationhuman ... TPSB2(64499)

安全信息

闪点(F)Not applicable
闪点(C)Not applicable

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