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Anti-MART-1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200737
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
6162.13 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Anti-MART-1 is produced in rabbit using a synthetic peptide corresponding to a sequence from the internal region of human MART-1 protein, conjugated to keyhole limpet hemocyanin (KLH). Melanoma antigen recognized by T-cells 1 (MART-1), also known as melan-A antigen, LB39-AA or antigen SK29-AA, is a type III signal-anchor protein that is localized mainly to the endoplasmic reticulum, the trans-Golgi network and melanosomes. MART-1 protein is expressed specifically in normal skin, retina, melanocyte cell lines and melanomas. It is a melanoma antigen recognized by T-cells and belongs to the melanocyte differentiation markers.

免疫原

synthetic peptide corresponding to a sequence from the internal region of human MART-1 protein, conjugated to KLH

应用

Anti-MART-1 antibody produced in rabbit has been used in:

  • immunoblotting
  • immunofluorescence
  • immunohistochemistry

生化/生理作用

Melanoma antigen recognized by T-cells 1 (MART-1) is specifically recognized by human leukocyte antigen (HLA-A2) restricted tumor-infiltrating T lymphocytes (TIL-1) in melanoma patients and is suggested to be involved in tumor progression. It is also involved in pigmentation process and is suggested as a candidate marker for albinism.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平200
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 ~13 kDa
species reactivityhuman
浓度~1.0 mg/mL
technique(s)immunoblotting: 2-4 μg/mL using human melanoma SK-Mel-28 cell line extract
immunofluorescence: 0.25-0.5 μg/mL using human melanoma SK-Mel-28 cell line
immunohistochemistry: 5-10 μg/mL using heat-retrieved formalin-fixed, paraffin-embedded human melanoma sections
UniProt登记号Q16655
运输dry ice
储存温度−20℃
Gene Informationhuman ... MART-1(2315)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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