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Anti-MAP2 Antibody, clone AP20, Biotin Conjugated

品牌
Sigma-Aldrich
货号
MAB3418B
规格纯度
clone AP20, from mouse, biotin conjugate
参考价格
7197.66 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The microtubule-associated protein 2 (MAP-2) is an abundant neuronal cytoskeletal protein that binds to tubulin, stabilizes microtubules (Herzog and Weber, 1978), and is an excellent marker for neurons. MAP-2 is essential for the development and maintenance of neuronal morphology (Matus, 1991). Three primary isoforms of MAP-2, the high molecular weight MAP2a and MAP2b, and the low molecular weight MAP2c (resulting from alternate splicing of the MAP2 gene), have been identified in neurours. (Chung et al., 1996). The low molecular weight isoform, MAP2c, is expressed in developing brain and is down-regulated during brain maturation, whereas the high molecular weight MAP2b is expressed in both developing and adult brain. The MAP2a appears only after brain maturation (Tucker, 1990). All these forms bind to microtubules through a domain near the carboxyl terminus that contains either three or four similar repeats of a 31-amino-acid motif (Lewis et al., 1988). MAP-2 together with MAP-4 and tau proteins belong to the family of thermostable proteins associated with microtubules.

免疫原

Bovine brain microtubule protein

应用

Anti-MAP2 Antibody, clone AP20, Biotin Conjugated is an antibody against MAP2 for use in ICC.
Immunocytochemistry Analysis: A 1:25 dilution from a representative lot detected MAP2 in rat E18 primary cortex cells.

质量

Evaluated by Immunohistochemistry in rat cortex tissue.

Immunohistochemistry Analysis: A 1:25 dilution of this antibody detected MAP2 in rat cortex tissue.

目标描述

The unconjugated parent antibody (Cat. No. MAB3418) has an observed molecular weight at ~230 kDa

外形

Purified mouse monoclonal IgG conjugated to Biotin in PBS with 0.1% sodium azide and 15 mg/mL BSA.
Protein G Purified

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss32160702
NACRESNA.41

产品性质

质量水平100
生物来源mouse
偶联物biotin conjugate
抗体形式purified antibody
antibody product typeprimary antibodies
克隆AP20, monoclonal
species reactivityrat
species reactivity (predicted by homology)mouse (based on 100% sequence homology), bovine (immunogen homology), human (based on 100% sequence homology), chicken (based on 100% sequence homology)
technique(s)immunocytochemistry: suitable
同位素/亚型IgG
UniProt登记号Q0IIA8
运输wet ice

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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