Anti-LTBP-3 Antibody

产品说明

一般描述

LTBP3 is a critical secreted protein that is part of the multi-protein complex that controls the action and release of the powerful developmental, immune, and signaling factor TGF-beta. LTBP3’s specific role appears to be in regulating the activation of the TGFB1 precursor complex. The removal of LTBP3 is essential for the activation of the complex. LTBP3 is expressed in many tissues including heart, skeletal muscle, prostate, testis, small intestine, ovary, pancreas, and liver. Recent research also demonstrates that LTBP3 plays important roles in many human carcinomas including breast, hepatic, and mesothelioma.

免疫原

KLH-conjugated linear peptide corresponding to human LTBP-3.

应用

Research Category
Cell Structure
This Anti-LTBP-3 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of LTBP-3.
Western Blotting Analysis: 2.0 µg/mL from a representative lot detected LTBP-3 in 10 µg of U2OS conditioned media.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected LTBP-3 in human prostate tissue.
Research Sub Category
Adhesion (CAMs)

质量

Evaluated by Western Blotting in mouse testis tissue lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected LTBP-3 in 10 µg of mouse testis tissue lysate.

目标描述

~240 kDa observed. The calculated molecular weight of this protein is 139 kDa, but can be observed at ~240 kDa due to high glycosylation.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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