Anti-LGN Antibody

产品说明

一般描述

LGN is also known as G-protein-signaling modulator 2 (GPSM2). LGN has an important role in cellular structure and spindle pole orientation. LGN also stabilizes the apical complex during neuroblast divisions. LGN defects lead to Chudley-McCullough syndrome as well as a multiple micronuclei phenotype due to chromosomal mis-segregation and cell division errors.

特异性

Other Homologies: Human (85% sequence homology), Chicken (75% sequence homology).

免疫原

GST-tagged recombinant protein corresponding to mouse LGN.

应用

Research Category
Cell Structure
Anti-LGN Antibody is a highly specific rabbit polyclonal antibody, that targets LGN & has been tested in western blotting.
Research Sub Category
Cytoskeleton
Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected LGN in mouse E16 brain tissue lysate.

质量

Evaluated by Western Blotting in rat E16 heart tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected LGN in rat E16 heart tissue lysate.

目标描述

~77 kDa observed. Uncharacterized bands may be observed at ~30 kDa, ~60 kDa, and ~70 kDa in some cell lysates.

外形

Rabbit polyclonal serum with 0.05% sodium azide.
Unpurified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
Heart tissue lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

产品性质

安全信息