产品说明
一般描述
Keratin 15 (KRT15)/cytokeratin 15, a type I keratin, belongs to the keratin (KRT) gene family. It is expressed in basal keratinocytes of stratified epithelium. KRT15 gene is located on human chromosome 17q21.2. Anti-Keratin 15 antibody detects endogenous levels of total Keratin 15 protein.
Anti-Keratin 15 Antibody detects endogenous levels of total Keratin 15 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human Keratin 15.
Immunogen Range: 1-50
应用
Anti-Keratin 15 antibody produced in rabbit has been used in: immunohistochemistry (1:100), immunofluorescence (1:100), immunostaining
生化/生理作用
Keratin 15 (KRT15) participates in maintaining cytoplasmic stability. It acts as a marker for skin stem cells in the hair follicle bulge. KRT15 plays a major role in epidermal homeostasis. It is associated with tumorigenesis. KRT15 might serve as a biomarker in predicting the prognosis of breast invasive carcinoma (BRCA) patients. Overexpression of the KRT15 gene is seen in squamous-cell carcinoma.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| NACRES | NA.41 |
产品性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | antigen 49 kDa |
| species reactivity | human, rat, mouse |
| 浓度 | ~1 mg/mL |
| technique(s) | ELISA: 1:20000 immunohistochemistry: 1:50-1:100 western blot: 1:500-1:1000 |
| NCBI登记号 | P19012 |
| UniProt登记号 | P19012 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... KRT15(3866) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
