Anti-KEAP1, clone 7G4B10 Antibody

产品说明

一般描述

Kelch-like ECH-associated protein 1, also known as Cytosolic inhibitor of Nrf2 or INrf2 or Kelch-like protein 19, and encoded by the gene name KEAP1 or INRF2 or KLHL19, acts as a substrate adapter protein for the E3 ubiquitin ligase complex and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome. KEAP1 shuttles between the cytoplasm and the nucleus and is widely expressed with high levels found in skeletal muscle.

免疫原

Purified recombinant fragment of human KEAP1 expressed in E. Coli

应用

Research Sub Category
Apoptosis - Additional
Research Category
Apoptosis & Cancer
Anti-KEAP1, clone 7G4B10 Antibody is an antibody against KEAP1 for use in IHC, flow cytometry & ELISA.
Flow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected KEAP1 in HeLa cells.

ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).

质量

Immunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected KEAP1 in bladder cancer and cerebellum tissues.

目标描述

70 kDa calculated

外形

Purified mouse monoclonal in PBS containing up to 0.1% sodium azide and 0.5% protein stabilizer.
Format: Purified
Protein G Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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