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Anti-IL1B (N-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2108882
规格纯度
affinity isolated antibody
参考价格
5258.35 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to inflammatory pain hypersensitivity. The gene encoding IL1B and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.

免疫原

Synthetic peptide directed towards the N terminal region of human IL1B

序列

Synthetic peptide located within the following region: MAEVPELASEMMAYYSGNEDDLFFEADGPKQMKCSFQDLDLCPLDGGIQL

外形

Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

产品性质

生物来源rabbit
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 17 kDa
species reactivity (predicted by homology)mouse, human, canine, rabbit, horse
浓度0.5 mg/mL
technique(s)immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-8 μg/mL
western blot: 1 μg/mL
NCBI登记号NM_000576
运输wet ice
储存温度−20℃
Gene Informationhuman ... IL1B(57396)

安全信息

储存分类代码10 - Combustible liquids
WGKnwg
闪点(F)Not applicable
闪点(C)Not applicable

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