产品说明
一般描述
Hyaluronan synthase 1 (HAS1) is one of three enzymes, located at the plasma membrane, that synthesizes the glycosaminoglycan hyaluronan or hyaluronic acid (HA). Hyaluronan is involved in cell proliferation, differentiation, angiogenesis, and tumor development, among other cellular processes.
特异性
This antibody recognizes the cytoplasmic domain of hyaluronan synthase 1.
免疫原
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human hyaluronan synthase 1.
Epitope: Cytoplasmic domain
应用
Research Sub Category
Apoptosis - Additional
Anti-hyaluronan synthase 1 Antibody, clone 12A2.3 is a highly specific mouse monoclonal antibody, that targets Hyaluronan synthase 1 & has been tested in western blotting & IHC.
Immunohistochemistry Analysis: A 1:200 dilution from a representative lot detected hyaluronan synthase 1 in human ovarian cancer tissues.
Research Category
Apoptosis & Cancer
质量
Evaluated by Western Blotting in HL-60 cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detects hyaluronan synthase 1 in 10 µg of HL-60 cell lysate.
目标描述
~70 kDa observed
外形
Purified by Ion-Exchange Chromatography
Purified mouse IgMκ supernatant in buffer containing PBS with 0.05% sodium azide.
Format: Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
HL-60 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
产品性质
质量水平 | 100 |
生物来源 | mouse |
抗体形式 | purified immunoglobulin |
antibody product type | primary antibodies |
克隆 | 12A2.3, monoclonal |
species reactivity | human |
technique(s) | immunohistochemistry: suitable western blot: suitable |
同位素/亚型 | IgMκ |
NCBI登记号 | NP_001514 |
UniProt登记号 | Q92839 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |