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Anti-Human IgE antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200741
规格纯度
clone GE-1, purified from hybridoma cell culture
参考价格
6729.16 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Anti-Human IgE antibody, Mouse monoclonal (mouse IgG2b isotype) is derived from the GE-1 hybridoma, produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with purified human IgE myeloma protein. Immunoglobulin E (IgE) is the least abundant immunoglobulin isotype in circulation. IgE is produced by plasma cells and is highly functional in the lung, skin and mucus membranes. Normal levels of IgE in serum are less than 1 μg/ml.

免疫原

purified human IgE myeloma protein

应用

Anti-Human IgE antibody, Mouse monoclonal has been used in various immunological techniques, including enzyme linked immunosorbent assay (ELISA), immunoblot, immunoprecipitation and IgE quantification using piezoelectric (Pz) crystal bioassay.

生化/生理作用

Immunoglobulin E (IgE) plays a critical role in allergic reactions and host protection from parasites. Serum IgE levels are highly elevated during an allergic reaction (such as atopic eczema, extrinsic asthma or hay fever, fungal and parasitic infection, atopic disease or primary immunodeficiency). Detection and measurement of total IgE concentrations is crucial for diagnosis, monitoring and treatment of allergy patients. In addition, the recognition and isolation of allergen-specific IgE can lead to progress in understanding of pathophysiologic mechanisms underlying IgE-associated allergic disorders.

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

基本信息

NACRESNA.46

产品性质

质量水平200
生物来源mouse
抗体形式purified from hybridoma cell culture
antibody product typeprimary antibodies
克隆GE-1, monoclonal
形式buffered aqueous solution
species reactivityhuman
浓度~1.0 mg/mL
technique(s)ELISA: 0.15-0.3 μg/mL using 1 μg/mL Human IgE myeloma for coating
immunoblotting: suitable
immunoprecipitation (IP): 1-2 μg/test using Human IgE myeloma
同位素/亚型IgG2b
运输dry ice
储存温度−20℃

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

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