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Anti-HLA-DP alpha 1 antibody, Rabbit monoclonal

品牌
Sigma-Aldrich
货号
SAB5500118
规格纯度
clone SP228, recombinant, expressed in proprietary host, affinity isolated antibody
参考价格
4731.57 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1) is a class II heterodimer comprising of a polymorphic β and an oligomorphic α chain. It is encoded by the gene mapped to human chromosome 6p21.33. HLA-DPA1 is generally expressed on a subset of Kupffer cells and resident macrophages in liver.
HLA-DP is an antigen receptor and one of the MHC class II proteins. HLA-DP is a heterodimer of an alpha and a beta chain. Both chains are type I transmembrane proteins with short cytoplasmic domains. It is expressed on antigen-presenting cells and a variety of other cell types, and is also expressed by various tumors such as melanoma, gastric carcinoma, breast carcinoma, ovarian carcinoma, and lymphoma.

免疫原

Synthetic peptide derived from human HLA-DP alpha1 protein.

应用

Anti-HLA-DP alpha 1 antibody, Rabbit monoclonal has been used in immunohistochemistry.

生化/生理作用

Major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1) alloreactivity is highly relevant in clinical transplantation. It plays an essential role in the presentation of viral antigens to CD4+ T helper (Th) lymphocytes. Studies have suggested that SNP (single nucleotide polymorphisms) of HLA-DP can result in chronic hepatitis B virus (HBV) infection.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

产品性质

生物来源rabbit
质量水平100
重组expressed in proprietary host
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆SP228, monoclonal
species reactivityhuman (tested)
technique(s)flow cytometry: 1:100
immunohistochemistry: 1:100
同位素/亚型IgG
UniProt登记号P20036
运输wet ice
储存温度2-8℃
Gene Informationhuman ... HLA-DPA1(3113)

安全信息

储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

Sigma-Aldrich

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