产品说明
一般描述
HBEGF is a growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. It is required for normal cardiac valve formation and normal heart function. HBEGF promotes smooth muscle cell proliferation. It may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. It also acts as a diphtheria toxin receptor.
免疫原
Synthetic peptide directed towards the N-terminal region of Human HBEGF
序列
Synthetic peptide located within the following region: FLAAVLSALVTGESLERLRRGLAAGTSNPDPPTVSTDQLLPLGGGRDRKV
外形
Supplied at 0.5 mg/ml in phosphate-buffered saline, 0.09% sodium azide
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
产品性质
| 生物来源 | rabbit |
| 偶联物 | unconjugated |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 形式 | buffered aqueous solution |
| 分子量 | 22 kDa |
| species reactivity (predicted by homology) | rat, pig, rabbit, canine, guinea pig, bovine, human, mouse |
| 浓度 | 0.5 mg/mL |
| technique(s) | western blot: 1 μg/mL |
| NCBI登记号 | NM_001945 |
| 运输 | wet ice |
| 储存温度 | −20℃ |
| Gene Information | human ... HBEGF(57396) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
| WGK | nwg |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
