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Anti-G6PD (AA 308-320) antibody produced in goat

品牌
Sigma-Aldrich
货号
SAB2500438
规格纯度
affinity isolated antibody, buffered aqueous solution
参考价格
7062.55 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

The gene encoding G6PD (glucose-6-phosphate dehydrogenase) is mapped to human chromosome Xq28 and spans 16.2 kb. One G6PD monomer is composed of 515 amino acids with a predicted molecular weight of 59,256 Da. The active enzyme exists as a dimer and contains an NADP molecule tightly bound to it.

免疫原

Peptide with sequence C-STNSDDVRDEKVK from the internal region of the protein sequence according to NP_000393.4 ; NP_001035810.1.

生化/生理作用

G6PD (glucose-6-phosphate dehydrogenase) enzyme catalyzes the oxidation of glucose-6-phosphate to 6-phosphogluconolactone, reducing NADP to NADPH. It therefore, catalyzes the first step of hexose monophosphate pathway (HMP). As it oxidizes glucose-6-phosphate, it confers protection against oxidative damage in erythrocytes. Its deficiency is highly heterogeneous, with around 190 variants being reported. The deficiency of G6PD was discovered while studying hemolytic anemia. G6PD also results in hereditary nonspherocytic hemolytic anemia.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.

基本信息

MDL编号MFCD00162329
NACRESNA.41

产品性质

质量水平100
生物来源goat
偶联物unconjugated
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
species reactivityrat, canine, human, mouse
technique(s)immunohistochemistry: suitable
indirect ELISA: suitable
western blot: suitable
UniProt登记号P11413
运输dry ice
储存温度−20℃
Gene Informationhuman ... G6PD(2539)

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319
预防措施声明P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2
储存分类代码12 - Non Combustible Liquids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable

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