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Anti-Glutathione Reductase antibody, Mouse monoclonal

品牌
Sigma-Aldrich
货号
SAB4200182
规格纯度
clone GR6, purified from hybridoma cell culture
参考价格
5045.46 *本价格含增值税费
促销
数量
-+
产品介绍:

产品说明

一般描述

Monoclonal Anti-Glutathione Reductase (mouse IgG1 isotype) is derived from the hybridoma GR6 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice immunized with a human Glutathione reductase recombinant protein. Glutathione reductase is a homodimeric enzyme containing one FAD molecule and NADPH binding domain per subunit. This gene is located on human chromosome 8p.

免疫原

mice immunized with a human Glutathione reductase recombinant protein. The corresponding proteins in rat and mouse share 86% and 85% homology, respectively.

应用

Monoclonal Anti-Glutathione Reductase antibody produced in mouse has been used in:

  • immunohistochemical
  • immunofluorescence studies
  • immunoblotting
  • immunoprecipitation

生化/生理作用

Glutathione reductase (GR) is a ubiquitous flavoenzyme involved in protecting cells from stress. GR catalyses the reduction of oxidized glutathione (GSSG) to glutathione (GSH). It is an essential component of the glutathione redox cycle, which maintains adequate levels of reduced cellular GSH. GSH serves as an antioxidant and also as an electron donor for glutathione peroxidases and a substrate for glutathione-S-transferases.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号MFCD01323367
NACRESNA.41

产品性质

质量水平200
生物来源mouse
偶联物unconjugated
抗体形式purified from hybridoma cell culture
antibody product typeprimary antibodies
克隆GR6, monoclonal
形式buffered aqueous solution
分子量antigen ~55 kDa
species reactivityhuman
浓度~1.0 mg/mL
technique(s)immunoprecipitation (IP): suitable
western blot: 2-4 μg/mL using whole extracts of human HepG2 cells.
同位素/亚型IgG1
UniProt登记号P00390
运输dry ice
储存温度−20℃
Gene Informationhuman ... GSR(2936)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

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